4E-BP eIF-4E binding protein
Abl Ableson protein tyrosine kinase
ACTR A histone acetyltransferase
AKT Cellular homolog of the v-akt oncogene, an S/T protein kinase
Apaf-1 Apoptotic protease activating factor-1
APC Adenomatous polyposis coli
APP b-amyloid precursor protein
APPs Acute phase proteins
ASK Apoptosis signal-regulating kinase
ATF1 Activating transcription factor 1, TREB36
ATF2 Activating transcription factor 2, CRE-BP1, CREB2
ATM Ataxia-telangiectasia mutated protein kinase
ATR ATM + Rad3-related protein kinase
Bcl B cell leukemia oncogene
BMP Bone morphogenetic protein
BRCA Breast cancer growth-suppressor protein
CAD Caspase-activated deoxyribonuclease
CaM-K Calcium/ calmodulin–dependent kinase
Cas Crk–associated substrate, p130CAS
Caspase Cysteine proteases with aspartate specificity
CBP CREB binding protein
Cdc2 Cell division cycle protein 2, CDK1
Cdc25c Cell division cycle protein 25, M-phase inducer phosphatase 3
Cdc34 Cell division cycle protein 34, an E2 ubiquitin conjugating enzyme
Cdc42 Cell division cycle protein 42, a G protein
CDK Cyclin-dependent kinase
Chk Checkpoint kinase
CHOP C/EBP homologous protein
Cip Cdk-interactin protein
CIS Cytokine inducible SH2-containing protein
CK1 Casein kinase 1
c-Myb Cellular homolog of the avian myeloblastosis virus oncogene
c-Raf Raf proto-oncogene S/T protein kinase
CREB cAMP response element-binding protein, CREB1
DAG Diacylglycerol
Daxx Fas death domain-associated protein
DNA-PK DNA-activated protein kinase
DP-1 Member of the E2F transcription factor family
DPC4 Deleted in pancreatic cancer locus 4, SMAD4
DR3 Death receptor 3
Dsh Dishevelled
dsRNA Double-stranded RNA
E2F Transcription factor family including E2F- and DP-like subunits
eEF Eukaryotic elongation factor
eIF Eukaryotic initiation factor
ELK1 Ets domain protein
eNOS Endothelial nitric oxide syntase, NOS-III
ER Endoplasmic reticulum
ER Estrogen receptor
ERK Extracellular signal-regulated kinase, MAPK
FADD Fas-associated protein with death domain
FAK Focal adhesion kinase
FKHR Forkhead in rhabdomyosarcoma
FLIPs FLICE (Caspase 8) inhibitory protein
FRAP FKBP12-rapamycin-associated protein
FRS2 FGF receptor stimulated, lipid-anchored Grb2 binding protein
GADD45 Growth arrest and DNA damage protein 45
GAP GTPase activating proteins
GAS IFNg-activating sequence
GCK Germinal center kinase
GCN2 General control of amino acid biosynthesis protein 2, a S/T kinase
GCN5 General control of amino acid biosynthesis protein 5, a histone acetyltransferase
GEF Guanine nucleotide exchange factor
GPCR G-protein coupled receptor
GRB2 Growth factor receptor-bound protein 2
GRIP Glucocorticoid receptor interacting protein, a histone acetyltransferase
GRK G-protein coupled receptor kinase
GSK-3b Glycogen synthase kinase-3b
HDAC Histone deacetylase
HMG High mobility group
HPK Hematopoietic progenitor kinase
HRI Hemin-regulated inhibitor, a S/T kinase
HSP27 Heat shock protein 27
IAP Inhibitor of apoptosis
ICAD Inhibitor of caspase-activated deoxyribonuclease
IkB Inhibitor of NF-kB
IKK IkB kinase
INK4 Inhibitor of CDK 4
IRS Insulin receptor substrate
ISRE Interferon-stimulating response element
Jak Janus-family tyrosine kinase
JNK Jun N-terminal kinase
KSR Kinase suppressor of Ras
LC8 Dynein light chain, cytoplasmic
M3/6 A dual-specificity phosphatase
MAPK Mitogen-activated protein kinase
MAPKAP-2 MAP kinase-activated protein kinase 2
MDM2 Murine double minute-2, a p53-associated oncogene
MEF2 Myocyte enhancer factor 2
MEK MAPK/ERK kinase, MAPKK
MEKK MEK kinase
MKP MAP kinase phosphatase
MLK Mixed lineage kinase
MNK MAP kinase-interacting kinase
MSK-1 Mitogen and stress-activated kinase 1
mTOR Mammalian target of rapamycin
MyoD Myogenic determination factor
Myt1 A dual-specificity protein kinase
NcoR Nuclear receptor corepressor
NFAT4 Nuclear factor of activated T cells 4
NF-kB Nuclear factor kappa B
NIK NF-kB Induced kinase
NLK NEMO-like kinase
p19Arf p19 alternative reading frame protein, a tumor suppressor
p300 A histone acetyltransferase
p53 Tumour suppressor protein that protects from DNA damage
PABP Poly(A) tail-binding protein 4
PARP Poly(ADP-ribose)polymerase, ADPRT
Pax Paxilin
PCAF p300/CBP-associated factor, a histone acetyltransferase
pCIP p300/CBP interacting protein, a histone acetyltransferase
PDK 3-phosphoinositide-dependent protein kinase
PEK Pancreatic eukaryotic initiation factor 2a-subunit kinase
PERK Type I transmembrane ER-resident protein kinase
PI3K Phosphoinositide-3 kinase
PIAS Protein inhibitors of activated STATs
PIP2 Phosphatidylinositol 3,4-bisphosphate
PIP3 Phosphatidylinositol 3,4,5-trisphosphate
PKA Protein kinase A
PKC Protein kinase C
PKR dsRNA-dependent serine/threonine protein kinase
PLCb Phospholipase Cb
PLCg Phospholipase Cg
Plk1 Polo-like kinase 1
PLP2A Phospholipase 2A
PP1 Phosphoprotein phosphatase 1
PP2A Phosphoprotein phosphatase 2A
PP2B Phosphoprotein phosphatase 2B
PPARg Peroxisome proliferator-activated receptor g
PR Progesterone receptor
PRAK p38 regulated activated kinase
PTEN Phosphatase and tensin homolog deleted on chromosome ten
PYK2 Proline-rich tyrosine kinase-2
RAIDD RIP-associated ICH/CED-3-homologous protein with a death domain
Rb Retinoblastoma protein, a tumor suppressor
RGS Regulator of G protein signaling
RIP Receptor-interacting protein
RSK Ribosomal S6 kinase
RTK Receptor tyrosine kinase
RXR Retinoid X receptor
S6 Small subunit ribosomal protein S6
S6K S6 kinase
SAPK Stress-activated protein kinase
SCF Skp-Cdc53-F-box ubiquitin ligase complex
Shc SH2-containing collagen-related proteins
SHP1 SH2-containing phosphatase 1
SHP2 SH2-containing phosphatase 2
Sin3 A transcriptional corepressor
SKP2 S-phase kinase associated protein 2
Smad Contraction of Sma and Mad (Mothers against decapentaplegic)
SMRT Silencing mediator of retinoic acid and thyroid hormone receptor
SOCS Suppressors of cytokine signalling
Sos Son of sevenless guanine nucleotide exchange factor
SOX SRY-related HMG box protein
SRC1 Steroid receptor coactivator 1, a histone acetyl- transferase
SRF Serum response factor
STAT Signal transducer and activator of transcription
TAFs TBP-associated factors
TAK TGFb-activated kinase
Tal Talin
tBid Truncated Bid
TBP TATA-binding protein
TCF T-cell factor, a Wnt signaling transcription factor
TF Transcription factor
TGF Transforming growth factor
TH Tyrosine hydroxylase
TIMP Tissue inhibitor of metalloproteinases
Tip60 HIV-1-Tat interactive protein, a histone acetyl- transferase
TNF Tumor necrosis factor
TR Thyroid hormone receptor
TRADD TNF receptor-1-associated death domain protein
TRAF2 TNF receptor-associated factor 2
VDAC Voltage-dependent anion channel
Wee1 A universal mitotic inhibitor kinase
Wnt Contraction of ‘Wingless’ and ‘Int’
